A vaccine, But no injection. Since the onset of the epidemic, planned
Govit-19 Patches are proliferating, testifying to a movement that could revolutionize the way vaccines are administered in the future. For some children who do not like syringes much, this technique will avoid some bursting tears. But above all, it has many advantages, especially in terms of distribution or increased performance.
The study of rats was published in the journal Friday Scientific advances, Showed promising results. Link used: 1cm x 1cm square, made of plastic, with more than 5,000 small peaks on its surface, “you can not see them,” explained virologist Dr. David Mல்லller, co-author of the study. University of Queensland, Australia. These tips are coated with the vaccine, which is deposited on it as it penetrates the skin.
Mice were patched (used for two minutes), others were vaccinated with needles. As for the previous one, “We got a very strong antibody response, including in the lungs, which is important Govit-192, Analyst in detail. The results obtained are often “surpassed” by the vaccine, he says.
Second, the efficacy of a dose was evaluated. By using an adjunctive drug that stimulates the immune system, rats are “not sick.” Vaccines are usually given by intramuscular injection. However, compared to skin, muscle does not have “many immune cells needed to support the vaccine”, Dr. Mல்லller explains.
In addition, the insertion of tips can cause minor injuries, which alert the body to a problem and thus stimulate the immune system. To the scientist, the advantages of the technique are clear: first, the vaccine is stable at 25 ° C for a month and 40 ° C for a week (compared to a few hours at room temperature for vaccinations). Pfizer Or Moderna). This allows for less dependence on the cold chain, which is “a challenge for developing countries.”
Simplicity and size
In addition, “Administration is incredibly easy”: No need for trained nursing staff. Purak Ostokanler, a professor of engineering at Carnegie Mellon University in Pittsburgh, USA, has been working on these links since 2007.
And he finds another advantage: “A small amount of vaccine, precisely injected into the skin, can develop immunity like a tendon injection,” he insists. An important factor in countries fighting over the dose. He can make 300 to 400 patches a day in his lab, but regrets not being able to experiment. Messenger RNA vaccines With Pfizer or Moderna, these groups are not authorized to do so.